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The Institute for Therapeutic Discovery, also known as TITD, which Dr. Dorsam is closely
affiliated with, has uncovered a new and potentially exciting "molecule" in the treatment of
allergies.
Dr. Dorsam devotes a lot of spare time reviewing the newest information in molecular
immunology, that is, the study of the body's immune system and its effect on disease. In much
of the recent research into allergies in people, a group of proteins has been identified that
appears to turn off the allergy cascade.
Our immune system, as well as our beloved cats and dogs, is split into two systems, Th1 and
Th2. The Th1 system is the part of your immune system responsible for fighting bacteria,
viruses, and other harmful antigens. The Th2 system is mostly responsible and active for
allergies, causing much of the physical symptoms of allergies both in people and dogs and cats.
A group of proteins has been identified that is involved in both systems. However, within this
group of proteins are literally hundreds of differing proteins that are responsive in each
immune system.
Suppressors of cytokine signaling proteins (SOCS) is that group of proteins. Within this group, several have been identified and quantitatively measured during bouts of allergic symptoms. SOCS-3 is one of the proteins that have been found to be present in high amounts during bouts of allergic disease. We have formulated a hormetic dose of SOCS-3 and have used it in a small number of dogs with allergies.
Because of the surprising early results, we are forming a field trial for its use.
We are currently searching for allergic dogs to try this new molecular medicine. The selected
individuals will be provided with the SOCS-3 molecule free of charge for the duration of the
trial. Blood from the selected patient will be frozen and sent to our laboratory in Providence,
Rhode Island for cytokine analysis and genome studies.
Our goal is to find an agent that has no side effects for the patient. It appears that SOCS-3,
so far, fits the bill.
For further details and enrollment information, please call Dr. Dorsam directly at the clinic.
(843-875-6303).
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